Molecular and biochemical analysis of signaling pathways that regulate cell proliferation and neural differentiation Chase Weidmann, Ph.D.Western blot is often used in research to separate and identify proteins.

Neuronal signaling and gene expression in the context of human neurologic and psychiatric disorders Anne Vojtek, Ph.D. Molecular regulation of key mediators of the mammalian stress response: Corticotropin-Releasing Hormone (CRH), CRH receptors and binding protein, and corticosteroid receptors dysregulation of the stress response in depression, anxiety disorders, and addiction Raymond Trievel, Ph.D.Ĭhemical and structural biology of enzymes that covalently modify histones, transcription factors, and other nuclear proteins current research focuses on elucidating the molecular mechanisms underlying the specificities of histone methyltransferases and demethylases and on developing new assays and reagents to characterize them Michael Uhler, Ph.D. Molecular mechanisms of redox, heme, and gas signaling pathways Structure-activity relationship and signaling pathways of neuropeptides and receptors of the RFamide peptide family and their role in regulating heart rate and muscle contractions Stephen Ragsdale, Ph.D. Protein interactions and modifications in living cells and animals mechanisms whereby cells and animals recognize and respond to synthetic chemicals James Morrissey, Ph.D.īiochemistry of the human blood clotting system structural studies of protein-membrane complexes Ruthann Nichols, Ph.D. Identification of signaling pathways, chromatin alterations, and gene expression programs that drive central nervous system regeneration using the retina as a model system Tom Kerppola, Ph.D. Chemical biology of hydrogen sulfide signaling, regulation of mammalian sulfur metabolism in health and disease, structural enzymology of human B12 trafficking proteins Uhn-Soo Cho, Ph.D.īiochemical and structural studies of kinetochore assembly, histone chaperones, and Sestrin-mediated mTORC1 regulation Daniel Goldman, Ph.D.

Cell and molecular biology khan academy